| Quanterall | |
| QuarkXR | |
| Quendoo | Sofia |
| R&D Solutions | Sofia |
| Ralev | |
| Ramus Medical Ltd | |
| Rank.bg | Sofia |
| Ravena Ltd | Sofia |
| Raytex | Sofia |
| Raz | |
| Re:benefit | Sofia |
| RE:TURN | |
| Rebellious Software | Sofia |
| Red Flask Studio Ltd | |
| Reflection Infosys Ltd | Veliko Tarnovo |
| Register.BG | Varna |
| Releva.AI | Sofia |
| Remotek | Varna |
| Rentaserver | Sofia |
| Rentila.com | Sofia |
| Republic of Bulgaria - Ministry of Transport, Information Technology and Communications | Sofia |
| Reset | Sofia |
| Revolution Technologies | Sofia |
| Right Direction | Sofia |
| Rila Solutions | Sofia |
| Rimex | Sofia |
| RISK Electronics | Sofia |
| Rizn Ltd | Sofia |
| RIZN Дизайн Студио | Sofia |
| Rosslyn Capital Partners | |
| Rousse Perl Mongers | Ruse |
| RS Consult BG Ltd | Sofia |
| RTS BG | Sofia |
| RubberDuck | |
| Rush Ltd | Ruse |
| rVertis | Sofia |
| S&T Bulgaria EOOD | Sofia |
| S3 Company | |
| Saikai | |
| SaitBG.com | Sofia |
| Santa | Sofia |
| Sappience | Sofia |
| Savana Soft | |
| Savov Design | Ruse |
| SBND Technologies | Sofia |
| SBS plc | Sofia |
| ScavaSoft | Varna |
| Schwarz IT Bulgaria | Sofia |
| SCIANT | Sofia |
| Security Bulgaria | Sofia |